Hepatology:
Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis in the USA
Yang A, Tincopa M, Tavaglione F et al. Prevalence of steatotic liver disease, advanced fibrosis and cirrhosis among community-dwelling overweight and obese individuals in the USA. Gut 2024; 73: 2045-2053. doi: 10.1136/gutjnl-2024-332917
Synergistic association of Sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction- associated steatotic liver disease
Mao X, Zhang X, Kam L, et al. Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease. Gut 2024; 73:2054-2061. doi:10.1136/gutjnl-2024-332481
Selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes
Roca Suarez A, Plissonnier M, Grand X, et al. TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism. Gut 2024; 73: 2012-2022. doi: 10.1136/gutjnl-2023-331396
Endoscopy:
Clinical consequences of computer-aided colorectal polyp detection
Sinonquel P, Eelbode T, Pech O, et al. Clinical consequences of computer-aided colorectal polyp detection. Gut 2024; 73: 1974-1983. doi:10.1136/gutjnl-2024-331943
IBD:
Serum biomarkers predicting short-term and mid/long-term relapse in patients with Crohn’s disease stopping infliximab
Pierre N, Huynh-Thu V, Baiwir D, et al. External validation of serum biomarkers predicting short-term and mid/long-term relapse in patients with Crohn’s disease stopping infliximab. Gut 2024; 73: 1965-1973. doi: 10.1136/gutjnl-2024-332648.
Coeliac Disease
Clinical outcomes of potential coeliac disease
Shiha MG, Schiepatti A, Maimaris S, et al. Clinical outcomes of potential coeliac disease: a systematic review and meta-analysis. Gut 2024;73:1944-1952. doi: 10.1136/gutjnl-2024-333110.
Reviewers
Dr Catherine Hsu, Gastroenterology Registrar, St Mary’s Hospital, Imperial College Healthcare NHS
Trust, London, UK
Dr Sam Withington, Gastroenterology Registrar, North West London, London, UK
Dr Kelly Chatten, Bolton NHS Foundation Trust, Bolton, UK
Dr Khurum Hakeem, Gastroenterology Registrar, University Hospital of North Durham, Durham, UK
Dr Abisoye Akintimehin, Gastroenterology Registrar London North West University Healthcare NHS Trust, London, UK
Dr James Sun, Pre-doctoral Clinical Research Excellence Fellow, Francis Crick Institute and King’s College London, London, UK
BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Editor in chief of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.
Funding
The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests:
None declared.
Provenance and peer review:
Not commissioned; internally peer reviewed.