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22 February 2024

February 2024 Gut Highlights

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Endoscopy

Predicting residual neoplasia after a non-curative gastric ESD

Morais R, Libanio D, Ribeiro M, et al. Predicting residual neoplasia after a non-curative gastric ESD: validation and modification of the eCura system in the Western setting: the W-eCura score. Gut 2024; 73: 105-17. doi: 10.1136/gutjnl-2023-330804

Read it here.


UK and Ireland Joint Advisory Group (JAG) consensus statements for training and certification in diagnostic endoscopic ultrasound (EUS)

Menabawey T, McCrudden R, Shetty D, et al. UK and Ireland Joint Advisory Group (JAG) consensus statements for training and certification in diagnostic endoscopic ultrasound (EUS). Gut 2024; 73: 118–130. doi: 10.1136/gutjnl-2023-329800

Read it here.


Gut Immunity

Dietary wheat amylase trypsin inhibitors exacerbate central nervous system (CNS) inflammation

Zevallos V, Yogev N, Hauptmann J, et al. Dietary wheat amylase trypsin inhibitors exacerbate CNS inflammation in experimental multiple sclerosis. Gut 2024; 73: 92-104. doi: 10.1136/gutjnl-2023-329562.

Read it here.


Oesophagus

Shorter-acting glucagon-like peptide-1 receptor agonists are associated with increased development of gastro-oesophageal reflux disease and its complications in patients with type 2 diabetes mellitus

Liu B, Udemba S, Liang K, et al. Shorter-acting glucagon-like peptide-1 receptor agonists are associated with increased development of gastro-oesophageal reflux disease and its complications in patients with type 2 diabetes mellitus: a population-level retrospective matched cohort study. Gut 2024; 73: 246-254. doi: 10.1136/gutjnl-2023-329651

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Pancreas

FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer

Canel M, Sławińska A, Lonergan D, et al. FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer. Gut 2024; 73:131-155. doi: 10.1136/gutjnl-2022-327927 

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Hepatology

Novel prognostic biomarkers in decompensated cirrhosis

Juanola A, Ma A, de Wit K On behalf of LiverHope Investigators, et al. Novel prognostic biomarkers in decompensated cirrhosis: a systematic review and meta-analysis. Gut 2024; 73: 156-165. doi: 10.1136/gutjnl-2023-329923.

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Reviewers

  • Dr Gaurav Nigam, NIHR Clinical Research Fellow, University of Oxford and Oxford University Hospitals, Oxford, UK
  • Dr Keith Pohl, South West Endoscopy Training Academy Leadership Fellow and Gastroenterology Registrar, Torbay and South Devon NHS Foundation Trust, Torquay, UK
  • Dr Nurulamin Noor, Clinical Lecturer in Gastroenterology, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.
  • Dr Anahita Sharma, Gastroenterology Registrar, Department of Gastroenterology, East Lancashire NHS Hospitals Foundation Trust, Burnley, UK
  • Dr Akudo Nwaogu, Gastroenterology Registrar, Department of Gastroenterology, King’s College Hospital NHS Trust, London, UK
  • Dr Brian Ho, Honorary Clinical Research Fellow and Gastroenterology Registrar, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK 

BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Deputy Editor of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.

Funding

The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

Competing interests

None declared.

Provenance and peer review

Not commissioned; internally peer reviewed.