IBD
Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis
Erkert L, Gamez-Belmonte R, Kabisch M, et al. Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis. Gut 2024; 73: 1618-1631. doi: 10.1136/gutjnl-2023-331622.
COLON
Risk of colorectal neoplasia after removal of conventional adenomas and serrated polyps
Polychronidis G, He M, Vithayathil M, et al. Risk of colorectal neoplasia after removal of conventional adenomas and serrated polyps: a comprehensive evaluation of risk factors and surveillance use. Gut 2024; 73:1675-1683. doi: 10.1136/gutjnl-2023-331729.
PANCREAS
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Brichkina A, Ems M, Suezov R, et al. DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer. Gut 2024; 73:1684-1701. doi: 10.1136/gutjnl-2023-331854.
HEPATOLOGY
High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy
Fan R, Zhao S, Niu J, et al. High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy. Gut 2024; 73: 1725-1736. doi:10.1136/gutjnl-2024-332182.
GUT MICROBIOTA
Multiple indicators of gut dysbiosis predict mortality in solid organ transplant recipients
Swarte J, Zhang S, Nieuwenhuis L, et al. Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients. Gut 2024; 73:1650-1661. doi: 10.1136/gutjnl-2023-331441.
STOMACH
The road to a world-unified approach to the management of patients with gastric intestinal metaplasia
Dinis-Ribeiro M, Shah S, El-Serag et al. The road to a world-unified approach to the management of patients with gastric intestinal metaplasia: a review of current guidelines. Gut 2024; 73:1607–1617. doi: 10.1136/gutjnl-2024-333029.
REVIEWERS
- Dr Nurulamin Noor, Clinical Lecturer in Gastroenterology, University of Cambridge and Cambridge University Hospitals, Cambridge, UK
- Dr Gaurav Nigam, NIHR Clinical Research Fellow, University of Oxford and Oxford University Hospitals, Oxford, UK
- Dr Akudo Nwaogu, Gastroenterology Registrar, Department of Gastroenterology, Kingston Foundation Hospital Trust, London, UK
- Dr Anahita Sharma, Gastroenterology Registrar, Department of Gastroenterology, Arrowe Park Hospital, Wirral, UK
- Dr Brian Ho, Honorary Clinical Research Fellow and Gastroenterology Registrar, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK
- Dr Keith Pohl, JAG Fellow and Gastroenterology Registrar, Torbay and South Devon NHS Foundation Trust, Torquay, UK
BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Deputy Editor of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.
FUNDING
The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
COMPETING INTERESTS
None Declared.
PROVENANCE AND PEER REVIEW
Not commissioned; internally peer reviewed.