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11 June 2024

June 2024 Gut Highlights

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Pancreas

A potential biological mechanism for the association between periodontal disease and pancreatic cancer – porphyromonas gingivalis

Saba E, Farhat M, Daoud A, et al. Oral bacteria accelerate pancreatic cancer development in mice Gut 2024; 73: 770-786. doi: 10.1136/gutjnl-2023-330941. 

Read it here.


Long-term follow-up study of necrotising pancreatitis

Hollemans R, Timmerhuis H, Besselink M et al. Long-term follow-up study of necrotising pancreatitis: interventions, complications and quality of life. Gut 2024; 73: 787-796. doi: 10.1136/gutjnl-2023-329735.

Read it here.


Hepatology

Glucagon-like peptide-1 receptor agonists and risk of major adverse liver outcomes in patients with chronic liver disease and type 2 diabetes

Wester A, Shang Y, Grip E, et al. Glucagon-like peptide-1 receptor agonists and risk of major adverse liver outcomes in patients with chronic liver disease and type 2 diabetes. Gut 2024; 73: 835–843. doi: 10.1136/gutjnl-2023-330962.

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Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease

Armandi A, Sanavia T, Younes R, et al. Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease. Gut 2024; 73(5): 825-834. doi:   10.1136/gutjnl-2023-330815

Read it here.


Oesophagus

Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance

Black E, Ococks E, Devonshire G, et al. Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis. Gut 2024; 73: 729-740. doi: 10.1136/gutjnl-2023-330721. 

Read it here.


Endoscopy

Standardised training for endoscopic mucosal resection of large non-pedunculated colorectal polyps to reduce recurrence 

Meulen L, Bogie R, Siersema P, et al. Standardised training for endoscopic mucosal resection of large non-pedunculated colorectal polyps to reduce recurrence (*STAR-LNPCP study): a multicentre cluster randomised trial. Gut 2024; 73: 741-750. doi:10.1136/gutjnl-2023-330020

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Reviewers

  • Dr Benjamin Zare, St Mark’s National Bowel Hospital & Academic Institute, London, UK
  • Dr Mie Thu Ko, NIHR Academic Clinical Fellow, University of East Anglia and Norfolk and Norwich University Hospital, Norwich, UK
  • Dr Benjamin Norton, Doctoral Research Student, Cleveland Clinic London (CCL) and University College London (UCL), London, UK
  • Dr Puneet Chhabra, Consultant Gastroenterologist, Calderdale and Huddersfield NHS Trust, Huddersfield, UK
  • Dr Mohsen Subhani, Nottingham University Hospitals NHS Trust, Nottingham, UK
  • Dr Ahmed El-Sayed, Gastroenterology Registrar, Hillingdon Hospital, Hillingdon, London, UK

BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Deputy Editor of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.

Funding

The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

Competing interests

None declared.

Provenance and peer review

Not commissioned; internally peer reviewed.