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15 October 2024

October 2024 Gut Highlights

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Endoscopy 

Diagnostic yield from symptomatic gastroscopy in the UK

Beaton D, Sharp L, Lu L, et al. Diagnostic yield from symptomatic gastroscopy in the UK: British Society of Gastroenterology analysis using data from the National Endoscopy Database. Gut 2024; 73: 1421-1430. doi: 10.1136/gutjnl-2024-332071. 

Read it here.


Hepatology

Association between primary hypothyroidism and metabolic dysfunction-associated steatotic liver disease: an updated meta-analysis

Mantovani A, Csermely A, Bilson J, et al. Association between primary hypothyroidism and metabolic dysfunction-associated steatotic liver disease: an updated meta-analysis. Gut 2024; 73: 1554-1561. doi: 10.1136/gutjnl-2024-332491.

Read it here.


Novel crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury

Yang Y, Xu L, Atkins C, et al. Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury. Gut 2024; 73:1543-1553. doi: 10.1136/gutjnl-2024-332033.

Read it here.


IBD

Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease (IBD)

Gabriëls R, van der Waaij A, Linssen M, et al. Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease. Gut 2024; 73:1454-1463. doi: 10.1136/gutjnl-2023-331696.

Read it here.


Helicobacter pylori 

Simplified Helicobacter pylori therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan- tetracycline dual therapy

Gao W, Liu J, Wang X, et al. Simplified Helicobacter pylori therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan-tetracycline dual therapy. Gut 2024; 73:1414-1420. doi: 10.1136/gutjnl-2024-332640.

Read it here.


Neurogastroenterology

Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis

Porcari S, Ingrosso M, Maida M, et al. Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis. Gut 2024; 73: 1431-1440. doi: 10.1136/gutjnl-2023-331835. 

Read it here.


Reviewers

  • Dr Khurum Hakeem, Gastroenterology Registrar, University Hospital of North Durham, Durham, UK
  • Dr Abisoye Akintimehin, Gastroenterology Registrar, Department of Gastroenterology, London North West University Healthcare NHS Trust, London, UK
  • Dr Sam Withington, Internal Medicine Registrar 3 (IMT3), Kingston Hospital NHS Foundation Trust, Kingston Upon Thames, London, UK
  • Dr James Sun, Gastroenterology Registrar, St Mark’s Hospital and Academic Institute, London North West Healthcare NHS Trust, London, UK
  • Dr Kelly Chatten, Gastroenterology Registrar, North West Deanery, UK
  • Dr Catherine Hsu, Gastroenterology Registrar, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK

BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Deputy Editor of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.

Funding

The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

Competing interests

None declared.

Provenance and peer review

Not commissioned; internally peer reviewed.