Gut microbiota
Proton pump inhibitors alter gut microbiota by promoting oral microbiota translocation
Xiao X, Zhang X, Wang J, et al. Proton pump inhibitors alter gut microbiota by promoting oral microbiota translocation: a prospective interventional study Gut 2024; 73: 1098-1109. doi: 10.1136/gutjnl-2023-330883
Hepatology
High-fat diet promotes liver tumorigenesis
Bu L, Zhang Z, Chen J, et al. High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT. Gut 2024; 73: 1156-1168. doi: 10.1136/gutjnl-2023-330826
Clinical, experimental and pathophysiological effects of Yaq-001 in patients with cirrhosis
Liu J, MacNaughtan J, Kerbert A, et al. Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbable, gut-restricted adsorbent in models and patients with cirrhosis. Gut 2024; 73: 1183-1198. doi: 10.1136/gutjnl-2023-330699.
Milk fat globule-epidermal growth factor 8 (MFGE8) prevents intestinal fibrosis
Lin S, Wang J, Mukherjee PK, et al. Milk fat globule-epidermal growth factor 8 (MFGE8) prevents intestinal fibrosis. Gut 2024; doi: 10.1136/gutjnl-2022-328608.
Coeliac disease
New Entity of Adult Ultra-Short Coeliac Disease
Raju S, Greenaway E, Schiepatti A, et al. New Entity of Adult Ultra-Short Coeliac Disease: The First International Cohort and Case-Control Study. Gut 2024;73: 1124-1130. doi: 10.1136/gutjnl-2023-330913.
Oesophagus
Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis
Gueguen E, Morsy Y, Mamie C, et al. Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis. Gut 2024; 73: 1076-1086. doi: 10.1136/gutjnl-2023-331743
Reviewers
- Dr Anahita Sharma, Gastroenterology Registrar, Department of Gastroenterology, East Lancashire NHS Hospitals Foundation Trust, Burnley, UK
- Dr Brian Ho, Honorary Clinical Research Fellow and Gastroenterology Registrar, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK
- Dr Akudo Nwaogu, Gastroenterology Registrar, Department of Gastroenterology, King’s College Hospital NHS Trust, London, UK
- Dr Nurulamin Noor, Clinical Lecturer in Gastroenterology, University of Cambridge and Cambridge University Hospitals, Cambridge, UK
- Dr Gaurav Nigam, NIHR Clinical Research Fellow, University of Oxford and Oxford University Hospitals, Oxford, UK.
- Dr Keith Pohl, South West Endoscopy Training Academy Leadership Fellow and Gastroenterology Registrar, Torbay and South Devon NHS Foundation Trust, Torquay, UK
BSG GUT Highlights is edited by Dr Philip J Smith, Honorary Consultant Luminal Gastroenterologist, Royal Liverpool Hospital, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon, Liverpool, UK. Dr Smith is the Digital and Education Editor of GUT, Deputy Editor of Frontline Gastroenterology and Associate Editor of BMJ Open Gastroenterology.
Funding
The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests
None declared.
Provenance and peer review
Not commissioned; internally peer reviewed.